Mutational analysis of p53 and PTEN in soft tissue sarcoma
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چکیده
منابع مشابه
Mutational analysis of p53 and PTEN in soft tissue sarcoma.
p53 and PTEN are the two most frequently mutated tumor suppressors in human cancer. However, literature on the effect of the joint inactivation of tumor-suppressor genes in soft tissue sarcoma (STS) is lacking. The purpose of this study was to investigate whether p53 and PTEN mutations play a role in the carcinogenesis of STS, as well as to evaluate their mutual role in STS pathogenesis. We scr...
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ژورنال
عنوان ژورنال: Molecular Medicine Reports
سال: 2011
ISSN: 1791-2997,1791-3004
DOI: 10.3892/mmr.2011.660